Photo of Ankit Gupta

Ankit Gupta

General Partner at Y Combinator

Ankit Gupta is a General Partner at Y Combinator, named in September 2025 after working with YC founders as a Visiting Partner. He co-founded Reverie Labs (YC W18), a machine learning drug discovery company, and was its CTO until Ginkgo Bioworks acquired its key assets in February 2024. He then led AI work at Ginkgo. He studied computer science at Harvard.

Now
General Partner, Y Combinator1
Co-founded
Reverie Labs (YC W18)4
Studied
Computer science (A.B. and S.M.), Harvard1
Based
Cambridge, Massachusetts2

In their words

I am a computer scientist and entrepreneur with 10 years of experience in machine learning and the life sciences. I was previously the co-founder and CTO of Reverie Labs, a small molecule therapeutics company that used machine learning to drive a pipeline of therapeutics in oncology. As a founder, I grew our company to a staff of 30, built a culture of technology and engineering that marries computer science with chemistry, and raised $31M from top investors to fund our internal therapeutics pipeline.

3

Experience

Y Combinator2024 – now
  1. General Partner2025 – now

    Garry Tan announced him as YC's newest General Partner on September 12, 2025. He works mainly from Cambridge, Massachusetts, where YC's original office was.2

  2. Visiting Partner32024 – 2025
Ginkgo Bioworks2024 – 2025
  1. Head of AI2024 – 2025

    Joined through Ginkgo's acquisition of Reverie Labs' assets. Worked on building and commercializing AI foundation models for antibodies, enzymes and mRNA.3

Reverie Labs2017 – 2024
  1. Co-founder and CTO2017 – 2024

    Reverie used machine learning to design brain-penetrant cancer drugs; its lead program was a CDK4/6 inhibitor in IND-enabling studies (the lab work needed before testing in people). He ran its machine learning, data science, software and infrastructure teams, and the company raised $31 million in total.3

Vicarious AI2017
  1. Researcher2017

    Deep learning research on computer vision and robotics tasks.3

Harvard John A. Paulson School of Engineering and Applied Sciences2015 – 2017
  1. Head Teaching Fellow, CS 181 (Machine Learning)32016 – 2017
  2. Teaching Fellow, CS 182 (Artificial Intelligence)32016
  3. Machine Learning Researcher2015 – 2017

    Deep learning research in the Harvard NLP group, advised by Alexander Rush, applying neural networks to gene regulation.3

Palantir Technologies2016
  1. Software Engineering32016
Google2015
  1. Software Engineering32015
Harvard Medical School2014
  1. Researcher2014

    Research intern at the Center for Cancer Computational Biology at the Dana-Farber Cancer Institute, analyzing genomic data.3

Bridgewater Associates2014
  1. Technology Associate32014

Education

Harvard UniversityJoint A.B. and S.M., earned in four years

A.B., Computer Science, magna cum laude with highest honors; Phi Beta Kappa3

Recognition

30 Under 30, Healthcare (2023)Dec 2022

Award · Forbes7

Direct Synthesis of Quantum Automata from FlowchartsApr 2012

Publication · 21st International Workshop on Post-Binary ULSI Systems3

Milestones

  1. Published a paper on quantum automata at the 21st International Workshop on Post-Binary ULSI Systems3
  2. Earned a joint A.B. and S.M. in computer science from Harvard6
  3. Presented research on dilated convolutions for genomic modeling at the ICML Workshop on Computational Biology in Sydney8
  4. Co-founded Reverie Labs, which joined Y Combinator's Winter 2018 batch3
  5. Reverie Labs raised a $25 million round6
  6. Named to Forbes 30 Under 30 in Healthcare for 2023, with co-founder Jonah Kallenbach7
  7. Ginkgo Bioworks acquired Reverie Labs' key assets; he joined Ginkgo to lead its AI work5
  8. Became a Visiting Partner at Y Combinator3
  9. Named a General Partner at Y Combinator2

Writing

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